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simbiology/matlab r2021a ![Development of aptamer’s whole-body <t>PBPK</t> modeling and fitting pharmacokinetics in the main metabolism organs. (A) Schematic illustration of the whole-body PBPK model for 68 Ga[Ga]-NOTA-SGC8. The PBPK model consists of 14 compartments as depicted in the scheme. (B) The general permeability-limited model equations and parameters for the PBPK modeling. (C to F) Whole-body PBPK model fit pharmacokinetics profiles (line) versus observed data (dots) of (C) aorta, (D) kidney, (E) liver and (F) spleen.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_2413/pmc10202413/pmc10202413__research.0126.fig.005.jpg) Simbiology/Matlab R2021a, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/simbiology/matlab r2021a/product/MathWorks Inc Average 90 stars, based on 1 article reviews
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Image Search Results
Journal: Research
Article Title: The First-in-Human Whole-Body Dynamic Pharmacokinetics Study of Aptamer
doi: 10.34133/research.0126
Figure Lengend Snippet: Development of aptamer’s whole-body PBPK modeling and fitting pharmacokinetics in the main metabolism organs. (A) Schematic illustration of the whole-body PBPK model for 68 Ga[Ga]-NOTA-SGC8. The PBPK model consists of 14 compartments as depicted in the scheme. (B) The general permeability-limited model equations and parameters for the PBPK modeling. (C to F) Whole-body PBPK model fit pharmacokinetics profiles (line) versus observed data (dots) of (C) aorta, (D) kidney, (E) liver and (F) spleen.
Article Snippet: A
Techniques: Drug discovery, Permeability